The mission of the PHO research team is to improve outcomes and long-term quality-of-life of children diagnosed with cancer, through clinical-translational laboratory research, participating in clinical studies and collecting relevant biomaterials (biobanking).
Vanhooren J*, Dobbelaere R*, Derpoorter C*, Deneweth L*, Van Camp L, Uyttebroeck A, De Moerloose B and Lammens T. (2023). CAR-T in the treatment of acute myeloid leukemia: barriers and how to overcome them. Hemasphere 7 (9): e937.
In this paper, we review the therapeutic challenges limiting the use of CAR T-cell therapy for AML and discuss promising novel strategies to overcome them.